Sesamoiditis is inflammation of the sesamoid bones. In humans it occurs on the bottom of the foot, just behind the large toe. There are normally two sesamoid bones on each foot; sometimes sesamoids can be bipartite, which means they each comprise two separate pieces. The sesamoids are roughly the size of jelly beans. In humans the sesamoid bones act as a fulcrum for the flexor tendons, the tendons which bend the big toe downward.

The sesamoid bones lie behind the bones of the fetlock, at the back of the joint, and help to keep the tendons and ligaments that run between them correctly functioning.

Usually periostitis (new bone growth) occurs along with sesamoiditis, and thesuspensory ligament may also be affected. Sesamoiditis results in inflammation, pain, and eventually bone growth.

Humans will also experience inflammation and pain. Sometimes the sesamoid bone will even fracture and can be difficult to pick up on X-ray. A bone scan is a better alternative.


Sesamoids act like pulleys. They provide a smooth surface over which the tendons slide, thus increasing the ability of the tendons to transmit muscle forces. The sesamoids in the forefoot also assist with weightbearing and help elevate the bones of the great toe. Like other bones, sesamoids can break (fracture). Additionally, the tendons surrounding the sesamoids can become irritated or inflamed. This is called sesamoiditis and is a form of tendinitis. It is common among ballet dancers, runners and baseball catchers.

In the horse sesamoiditis is generally caused by excess stress on the fetlock joint. Conformation that promotes sesamoiditis include long pasterns or horses with long toes and low heels.

In the human excessive forces caused by sudden bending upwards of the big toe, high heels, or a stumble can contribute to sesamoiditis. Once the sesamoid bone is injured it can be very difficult to cure because every time you walk you put additional pressure on the sesamoid bone. Treatment in humans consists of anti-inflammatory medication, cortisone injections, strapping to immobilize the big toe and orthotics with special accommodations to keep pressure off the affected bone.

human sesamoid bones


    • Pain is focused under the great toe on the ball of the foot. With sesamoiditis, pain may develop gradually; with a fracture, pain will be immediate.

    • Swelling and bruising may or may not be present.

    • You may experience difficulty and pain in bending and straightening the great toe.

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During the examination, the physician will look for tenderness at the sesamoid bones. Your doctor may manipulate the bone slightly or ask you to bend and straighten the toe. He or she may also bend the great toe up toward the top of the foot to see if the pain intensifies.

Your physician will request X-rays of the forefoot to ensure a proper diagnosis. In many people, the sesamoid bone nearer the center of the foot (the medial sesamoid) has two parts (bipartite). Because the edges of a bipartite medial sesamoid are generally smooth, and the edges of a fractured sesamoid are generally jagged, an X-ray is useful in making an appropriate diagnosis. Your physician may also request X-rays of the other foot to compare the bone structure. If the X-rays appear normal, the physician may request a bone scan.

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Treatment is generally nonoperative. However, if conservative measures fail, your physician may recommend surgery to remove the sesamoid bone.


    • Stop the activity causing the pain.

    • Take aspirin or ibuprofen to relieve the pain.

    • Rest and ice the sole of your feet. Do not apply ice directly to the skin, but use an ice pack or wrap the ice in a towel.

    • Wear soft-soled, low-heeled shoes. Stiff-soled shoes like clogs may also be comfortable.

    • Use a felt cushioning pad to relieve stress.

    • Return to activity gradually, and continue to wear a cushioning pad of dense foam rubber under the sesamoids to support them. Avoid activities that put your weight on the balls of the feet.

    • Tape the great toe so that it remains bent slightly downward (plantar flexion).

    • Your doctor may recommend an injection of a steroid medication to reduce swelling.

    • If symptoms persist, you may need to wear a removable short leg fracture brace for 4 to 6 weeks.

Fracture of the Sesamoid

    • You will need to wear a stiff-soled shoe or a short, leg-fracture brace.

    • Your physician may tape the joint to limit movement of the great toe.

    • You may have to wear a J-shaped pad around the area of the sesamoid to relieve pressure as the fracture heals.

    • Pain relievers such as aspirin or ibuprofen may be recommended.

    • It may take several months for the discomfort to subside.

    • Cushioning pads or other orthotic devices are often helpful as the fracture heals.